Physics of multicellular systems – collective cell dynamics in cancer and tissue organization

Where and when:

October 31-November 1, 2024

Het Trippenhuis

Kloveniersburgwal 29

1011 JV Amsterdam

Confirmed speakers:

Jona Kayser, Max Planck Institute for the Science of Light, Erlangen DE

Kevin Cheung, Fred Hutchinson Cancer Center, Seattle WA USA

Ben Fabry, Friedrich-Alexander-Universität, Erlangen DE

Cécile Sykes, l'Ecole Normale Supérieure, Paris FR

Danijela Vignjevic, Institut Curie, Paris FR

Josef Käs, University of Leipzig, Leipzig DE

Giorgio Scita, University of Milan, Milan IT

Silke Henkes, Leiden University, Leiden NL

Sara Wickström, Helsinki University, FI and MPI for Molecular Biomedicine, Münster DE

Roberto Mayor, University College London, London UK

Lisa Manning, Syracuse University, Syracuse NY USA

David Beebe, University of Wisconsin-Madison, Madison WI USA

Erik Danen, LACDR, Leiden University NL

Peter Friedl, Radboud University, Nijmegen NL

Jaap den Toonder, TU Eindhoven, Eindhoven NL

Gijsje Koenderink, TU Delft, Delft NL

~14 talks selected from abstracts & ample time for poster sessions

Further info & preliminary program, see next pages

Physics of multicellular systems – collective cell dynamics in cancer and tissue organization

Organizers: Erik Danen, Thomas Schmidt, Luca Giomi (Leiden Univ.), Peter Friedl (Radboud Univ. Nijmegen), Gijsje Koenderink (TU Delft), Martijn Gloerich (UMC Utrecht), Jaap den Toonder & Liesbeth Janssen (TU Eindhoven)

Contribution: €100,- including 2xlunch and social evening.
Registration and payment: https://shop.paylogic.com/7d7c6dafd9804701916b6b034b5147d3
After payment you can create your own invoice
Abstract submission: m.e.koerselman@lacdr.leidenuniv.nl

08:30 - 09:00 Walk in

09:00 - 09:15 Opening remarks

Tissue organization & development

09:15 - 09:45 Silke Henkes (NL) -- tension-regulated tissue organization

09:45 - 10:15 Roberto Mayor (UK) -- Collective migration during embryo development

10:15 - 10:30 abstract

10:30 - 10:45 abstract

10:45 - 11:30 Coffee & posters

Cancer & the TME

11:30 - 12:00 Daniela Vignjevic (FR) -- Self-organizing principles driving tumor hierarchy and stemness

12:00 - 12:30 Erik Danen (NL) - Modeling cell interactions in the TME

12:30 - 12:45 abstract

12:45 - 13:00 abstract

13:00- 14:15 lunch & posters

Cell & tissue mechanics

14:15 - 14:45 Cécile Sykes (FR) -- Phase diagrams, phase portraits and trajectories in cell biophysics

14:45 - 15:15 Jona Kayser (DE) – Cell packing and cellular evolution

15:15 - 15:30 abstract

15:30 – 1545 abstract

15:45 - 16:30 Tea & posters

Physics of cancer

16:30 - 17:00 Josef Käs (DE) -- Does Oncology need Physics of Cancer?

17:00 - 17:30 Kevin Cheung (US) -- Cell and tissue state transitions regulating collective metastasis

17:30 - 17:45 abstract

17:45 - 18:00 abstract

18:00 Evening program

Thursday Oct 31

Preliminary program

08:45 - 09:15 Walk in

Mechanics in development and cancer

09:15 - 09:45 Sara Wickström (FI) -- Mechanical regulation of cell states

09:45 - 10:15 Lisa Manning (US) – Mechanics in tissue development

10:15 - 10:30 abstract

10:30 - 10:45 abstract

10:45 - 11:30 Coffee & posters

Cancer cell migration

11:30 - 12:00 Giorgio Scita (IT) -- Tissue fluidification in the pathobiology of breast cancer

12:00 -12:30 Peter Friedl (NL) -- Collective invasion plasticity and therapy response

12:30 - 12:45 abstract

12:45 - 13:00 abstract

13:00- 14:15 Lunch & posters

Cell & tissue mechanics

14:15 - 14:45 Ben Fabry (DE) – biophysics of cell migration

14:45 - 15:15 Gijsje Koenderink (NL) -- Cytoskeletal cross talk

15:15 - 15:30 abstract

15:30 – 1545 abstract

15:45 - 16:30 Tea & posters

Advanced models

16:30 - 17:00 David Beebe (USA) -- Microphysiological systems enable novel studies of cell behavior and signaling

17:00 - 17:30 Jaap den Toonder (NL) -- Microfluidics models for cancer

17:30 - 17:45 abstract

17:45 - 18:00 Closing remarks

Preliminary program

Friday Nov 01